With each player in a game of Scrabble or Words With Friends getting 7 letters at a time on their rack, 6-letter words can play a huge part in deciding who will win and who will lose a game.
The 6-letter words containing AI on this list are worth 9.3 points on average.
But the best of the lot is worth a grand total of 22 in a game of Scrabble and that word is JEZAIL.
If none of the 469 words on this list meet the criteria that you are looking for then you may find some success with similar lists: 6-letter words starting with AI, 6-letter words ending in AI and words with AI.