With each player in a game of Scrabble or Words With Friends getting 7 letters at a time on their rack, 6-letter words can play a huge part in deciding who will win and who will lose a game.
The 6-letter words containing EN on this list are worth 9.4 points on average.
But the best of the lot is worth a grand total of 27 in a game of Scrabble and that word is FIZZEN.
If none of the 1139 words on this list meet the criteria that you are looking for then you may find some success with similar lists: 6-letter words starting with EN, 6-letter words ending in EN and words with EN.